Chronic Lymphocytic Leukemia Research Consortuim
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Research into new ways of treating Chronic Lymphocytic Leukemia is going on all the time. As no current treatments for leukemia cure all the patients treated, doctors dealing with the disease are continually looking for new ways to treat it.

Clinical Research Core

Michael J. Keating, M.D., B.S.
M.D. Anderson Cancer Center

William W. Wierda M.D., Ph.D.
M.D. Anderson Cancer Center

Kanti R. Rai, M.D.
North Shore-Long Island Jewish Medical System

Neil E. Kay, M.D.
Mayo Clinic

Jennifer Brown, M.D., Ph.D.
Dana-Farber Cancer Institute


Research-Based Objectives

  1. Clinical trial development linked with correlative studies. Design, data collection, and analyses of new protocols developed by CRC investigators will be fully supported
  2. Develop predictive models, identify, and confirm prognostic factors for clinical endpoints including time to treatment, response to treatment, time to progression, and survival
  3. Develop systems for data exchange between different databases in order to increase access to available clinical data.

Core-Based Objectives

  1. Further develop CIMS and patient database(s) to assure complete and accurate clinical and laboratory data
  2. Provide a clinical trial-specific structure to utilize CIMS for CRC clinical trials
  3. Provide a platform in which CRC investigators performing laboratory studies interface with Biostatistics Core B to request clinical information for analyses
  4. Coordinate CRC Clinical Advisory Committee (CAC) activities
  5. Maintain and coordinate regulatory documentation including IRB correspondence, SAE reports, FDA correspondence and audit results for CRC clinical sites

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